"And upholding all things by the word of His power..." (Hebrews 1:3)
I think one of the biggest struggles a man goes through is that of trusting God. As man is hardwired to take control and conquer and establish order via submission, it follows that if any man truly wants to know God, He must, must lay down this most primal aspect to His person and character in order to know Jesus.
"Then said Jesus unto His disciples, If any man will come after me, let him deny himself, and take up his cross, and follow me." (Matthew 16:24)
Man, boy, dude
The only thing that I can truly give Jesus is myself. I cannot affect anything nor really maintain the state of things without His help. He says it plainly in John's gospel (John 15:5). "I am the vine, ye are the branches: he that abideth in me, and I in him, the same bringeth forth much fruit..." Okay, now check this out: "for without me ye can do nothing." This might seem passe, but the King James pronouns much of what is directed out from God to the masses as identified under a masculine pronoun. You find in the original Hebrew and Greek, the words for "man" (adam. anthropos, respectively) transliterated exactly. So what is a man to do? I would say that he should take everything he is, and give it to Jesus. Jesus may be a man, but He is so much more. And it isn't that I'm looking to attain some higher level of masculinity. More testosterone and muscle and hubris, no. Just that I want to become as like Jesus as I possibly can. And it's inside on a spiritual and also mental level that I want to affect and perfect. To where my inherent drive is tempered with love and patience and compassion. A willingness to follow where I feel He's leading and to "bring into captivity every thought to the obedience of Christ." (2 Corinthians 10:5) This is what it means to be a man. Physiology notwithstanding.
"Who is a wise man and endued with knowledge among you? Let him shew out of a good conversation his works with meekness of wisdom." (James 3:13)